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Fracture Risk Assessment Tool (FRAX) underestimates fracture risk for people with mental illness

The World Health Organization’s Fracture Risk Assessment Tool (FRAX) underestimates the 10-year fracture risk for people with mental illness—notably depression—and those taking drugs for psychiatric conditions—notably selective serotonin reuptake inhibitors (SSRIs), mood stabilizers (lithium, anticonvulsants, atypical antipsychotics), other antipsychotics, or benzodiazepines, claims new research.